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Faculty

 

Yufeng Wei

Yufeng Wei

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Department: Chemistry
Office Location: S-423
Phone: 201-200-2309
Email: ywei@njcu.edu
Area of Interest/Research:

Dr. Wei’s research is focuses on the understanding of the molecular regulations of key biological pathways that determine the death or survival of tumor cells. This regulatory mechanism could also affect HIV-1 infiltration into the central nervous system through the blood-brain barrier. Using advanced spectroscopic (NMR and fluorescence) and biophysical techniques (DSC, ITC, SPR), combined with molecular dynamics simulations, his lab explores the crucial protein-protein interactions (PPIs) that control apoptosis (programmed cell death) and the mitogen-activated protein (MAP) kinase pathway (cell proliferation, migration and invasion, and tumor progression). He expects that this new insight into the mechanistic regulations will inform novel therapeutics to cancers and HIV-1 infections.

Skills

  • NMR spectroscopy
  • Fluorescence protein expression and purification
  • Molecular dynamics protein structure
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